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THE ANTI-OXIDANT ACTIVITY OF EXTRACTS AND FRACTIONS OF CHROMOLAENA BULLATA (KLATT) KING & ROBINSON


Información de la publicación

Información de la publicación
Tipo de publicación

Científica

Tipología

Investigación y estudios

Medio de publicación
  • Digital: Revista digital

Resumen

 Abstract

The current trend in this field is the search for compounds derived from our vegetal species which have an anti-oxidant activity that is beneficial for human health. Colombia has a number of species known as field weeds (arvenses), like those of the Chromolaena genus, which are reported to have a high content of flavonoids. This study evaluated the anti-oxidant activity of extracts and fractions of the aerial parts of Chromolaena bullata plants found in the departments of Cundinamarca and Boyacá in Colombia, using the DPPH● and ABTS●+. For that purpose, extracts and fractions were obtained with the use of the Soxhlet method with solvents of different polarities of flowers and leaves. This study evaluated concentrations of 1, 10, 62.5, 100 and 250 mg of the extract or fraction per/ liter of MeOH, obtaining percentages for the capture of DPPH● radicals of between 46.16 ± 0.7 and 92.21 ± 0.2, at 250 ppm, for the leaves, and between 46.19 ± 3.1 and 91.13 ± 0.3, at 250 mg/L of MeOH, for the flowers. With the ABTS●+ method, the range was between 90.14 ± 1.1 and 99.55 ± 0.2, at 250 mg/L of MeOH, for the leaves, and 64.65 ± 1.0 and 97.84 ± 0.6, at 250 mg/L, for the flowers. The study found that the methanolic fractions of flowers and leaves showed a high anti-oxidant activity when evaluated by the ABTS●+ y DPPH● techniques and that the ABTS●+ showed a greater sensitivity.

Autores

Rodríguez A. Oscar E.1 , Torrenegra G. Rubén D.2
1Department of Environmental Engineering, Faculty of Engineering, Universidad El Bosque, Bogotá, Colombia
2Faculty of Science, Universidad de Ciencias Aplicadas y Ambientales, UDCA, Bogotá, Colombia
rodriguezoscare@unbosque.edu.co

Registro ISSN

1827-8620

Fecha de publicación 30 de abril de 2017
Fecha de aceptación 06 de marzo de 2017
Medio indexado (nombre)

pharmacologyonline

Bases de datos donde está referenciada

scopus

Información de apoyo a la difusión
Documentos PhOL_2017_1_A010_Rodriguez_98_105.pdf

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